SeZvipfeko zvemishonga, kunaka kwezviputi zvisina chinhu zvinogadzirisa zvakananga kuchengeteka, kushanda, uye kugadzikana kwechigadzirwa chekupedzisira chemishonga. Kana aya anoratidzika kunge akareruka macapsule shells aine hurema asati azadzwa nemushonga, anogona kuve njodzi huru yakavanzika kumhando yezvinodhaka. Uku kukanganisa kunobva kwete chete kubva mukutsauka kwemaitiro panguva yekugadzira asi zvakare zvine hukama zvakanyanya nekusakwana kwekutonga kwezvakatipoteredza panguva yekuchengetedza nekufambisa. Ivo vanogona kukamurwa zvakanyanya mumhando mitatu mikuru: yemuviri, makemikari, uye biological.
Kuremara kwemuviri ndiyo yakanyanya intuitive uye yakajairika mhando. Yekutanga ndeye Fragility kana Brittleness. Iyo inokwanisa capsule shell inofanirwa kuve ine mwero elasticity uye kuoma. Iyo brittle capsule inonyanya kuputika panguva yekufambisa kana nzira yekuzadza, zvichitungamira mukudonha kwezvinodhaka uye dosing isiriyo. Zvinotevera Kusaenzana Kukora kana Mhepo Mabhabhu, ayo anogona kukanganisa kunyungudika kwekapisi, zvichikonzera kuti mushonga uburitswe nekukasira kana kuti zvishoma nezvishoma mumuviri, zvichikanganisa kurapa kwayo. Uyezve, Dimensional Deviation inyaya yakakomba yekugadzira. Kana zviyero zvechivharo nemuviri zvisingaenderane zvakanaka, zvinoguma nechisimbiso chisina kunaka, zvichiita kuti vaparadzanise nyore nyore panguva yekuchengetedza uye kuisa mushonga kune zvakatipoteredza, zvichiita kuti vaparadze. Kusakwana kwepamusoro seMakwara, Spots, kana Discoloration haisi nyaya dzekunaka chete; vanogonawo kuva zviratidzo zvezvinhu zvisina kuchena kana kusvibiswa panguva yekugadzira.
Kukanganisika kwemakemikoro kunonyengera asi kune ngozi zvikuru. Nheyo yenyaya yacho iri mumhando yegelatin. Kana zvinhu zvakaderera, zvakaita se-zvisiri zvemishonga{3}yegiredhi yegelatin, zvikashandiswa, kana kuti kana zvinhu zvinokuvadza zvikaunzwa panguva yekugadzirwa, mateko emakapisi anogona kunge aine mwero wakawandisa wesimbi inorema (sechromium), yakasara titanium dioxide, kana zvinonyungudutsa zvinokuvadza. Izvi zvemakemikari zvinhu zvinogona kuungana mumuviri wemunhu nekufamba kwenguva, zvichikonzera kukuvadza kunhengo dzakaita sechiropa neitsvo. Chiitiko cheToxic Capsule chakakatyamadza nyika makore akati wandei apfuura chaive mhedzisiro yekushandiswa kwemaindasitiri gelatin, izvo zvakakonzera kuwanda kweiyo heavy metal chromium uye yakaunza njodzi huru kuhutano hweveruzhinji. Pamusoro pezvo, kana iyo pH kukosha kwekapule shell isiri kusvika pachiyero, inogona kuita nemimwe alkaline kana acidic zvinodhaka, zvichiita kuti vadzikise kana kuburitsa zvinhu zvinokuvadza.
Biological defects inonyanya kureva kusvibiswa kwehutachiona. Yakapfuma muprotein uye hunyoro, isina chinhu capsules inzvimbo yakanaka yekukura kwehutachiona. Kana hutsanana hwenzvimbo yekugadzira husina mwero kana kuti nharaunda yekuchengetera yakanyorova zvakanyanya, macapsule shells anogona nyore kusvibiswa nebhakitiriya, mold, kana kunyange pathogenic microorganisms. Makapisi asina chinhu akasvibiswa netwupukanana haangoshatise mushonga chete, izvo zvinogona kukonzera hutachiona hwematumbo kana kusawirirana muvarwere, asi metabolic byproducts (senge mycotoxins) zvakare ine carcinogenic yakanyanya. Naizvozvo, kuita yakasimba microbial muganho bvunzo pamakapisi asina chinhu chikamu chakakosha chekutonga kwemhando.
Mukupedzisa, kukanganisa kwema capsules asina chinhu ari kure nekuve nyaya yakapusa yekuonekwa kwakashata. Kubva pakutendeseka kwemuviri uye kuchena kwemakemikari kusvika kukuchengetedzwa kwebhayoloji, chero kutarisa mune chero yeiyi nzvimbo kunogona kudyara yakavanzika yekuchengetedza njodzi. Nekuda kweizvozvo, makambani emishonga anofanirwa kuita ongororo yakasimba uye kuongororwa pakusarudza vasina chinhu capsule suppliers, nepo masangano anodzora anofanirwa kuramba achisimbisa utariri kuona kuti iyi diki diki yeKupfeka inoshanda sechivharo chakasimba chinodzivirira hutano hwevarwere, pane inogona kuve Nguva Bhomba yenjodzi dzakavanzwa. Kana paine mimwe mibvunzo nezve capsules isina chinhu, unogamuchirwa kubata KornnacCaps.
